Organic, Bioorganic, & Medicinal Chemistry
We are firmly convinced that synthetic organic chemistry is not only a critical enabling technology for medicine and public health, but also a field worthy of continued, energetic, and creative investigation. Research in the Carlier Group is therefore directed in both directions.
Enantioselective synthesis of drug-like molecules via axially chiral enolates
On the synthetic side, our interest in axially chiral enolates has led us to study the enantioselective ring-contraction which can be viewed on page two of the research summary. These enantiopure quinolone derivatives may prove to be a useful new scaffold for medicinal chemistry.
The Malaria Problem
Current Funding Source